Dissociable executive functions in behavioral variant frontotemporal and Alzheimer dementias
نویسندگان
چکیده
منابع مشابه
Executive function in progressive and nonprogressive behavioral variant frontotemporal dementia.
BACKGROUND Recent studies suggest that behavioral variant frontotemporal dementia (bv-FTD) patients differ in their prognosis with fast-progressing and very slow-progressing cases. We investigated executive and behavioral profiles of progressive and nonprogressive bv-FTD patients to establish diagnostic markers discriminating the two groups. METHODS A range of neuropsychological and behaviora...
متن کاملClinical and psychometric distinction of frontotemporal and Alzheimer dementias.
BACKGROUND A proportion of patients who meet the National Institute of Neurological and Communicative Disorders and Stroke and the Alzheimer's Disease and Related Disorders Associations criteria for Alzheimer disease (AD) have frontotemporal lobar degeneration (FTLD) confirmed at autopsy, with or without concomitant AD. Thus, the clinical phenotypes of the 2 disorders may overlap. OBJECTIVE T...
متن کاملBehavioral-variant frontotemporal dementia
OBJECTIVE To identify distinct behavioral phenotypes of behavioral-variant frontotemporal dementia (bvFTD) and to elucidate differences in functional, neuroimaging, and progression to residential care placement. METHODS Eighty-eight patients with bvFTD were included in a cluster analysis applying levels of disinhibition and apathy (Cambridge Behavioural Inventory-Revised) to identify phenotyp...
متن کاملA comparison of memory and executive functions in Alzheimer disease and the frontal variant of frontotemporal dementia.
This study examined memory and executive functions of switching and distributing attention in 25 Alzheimer patients (AD), 9 patients with frontal variant of frontotemporal dementia (fvFTD), and 25 healthy older people, as a control group, in three tasks: verbal digit span, Brown-Peterson (B-P) task, and dual-task. No differences were found in digit span. Qualitative analysis of errors in the B-...
متن کاملDivergent social functioning in behavioral variant frontotemporal dementia and Alzheimer disease: reciprocal networks and neuronal evolution.
Behavioral variant frontotemporal dementia (bvFTD) disrupts our most human social and emotional functions. Early in the disease, patients show focal anterior cingulate cortex (ACC) and orbital frontoinsula (FI) degeneration, accentuated in the right hemisphere. The ACC and FI, though sometimes considered ancient in phylogeny, feature a large bipolar projection neuron, the von Economo neuron (VE...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Neurology
سال: 2013
ISSN: 0028-3878,1526-632X
DOI: 10.1212/wnl.0b013e318296e940